Ukusebenza kwekhambi lokwelapha elwa namagciwane kuxhomeke ekhonweni lamagciwane okudala ukumelana nemithi. Ukwelapha izifo, odokotela baphoqelelwa ukuthi basebenzise umphumela ohlangene wemithi elwa namagciwane amaningi ngasikhathi sinye.
Ukusetshenziswa ngasikhathi sinye kwezidakamizwa ezi-2 noma ezi-3 ezinemikhombandlela ehlukene yesenzo kuvimbela ukukhula kokumelana kuma-pathogens futhi kubuyisele ukuzwela ekwelashweni. Ngakho-ke, ekuqothulweni kwengqimba ye-Helicobacter pylori gar ebhekele ukuthuthukiswa kwezilonda esiswini kanye nezinye izindlela ze-gastritis, inhlanganisela ye-Amoxicillin neClithithycin iyasetshenziswa.
Isici se-Amoxicillin
I-antibiotic ye-penicillin ibonakala ngethala elibanzi lokwelapha, izinga eliphansi lokumelana nokufakwa okuhle esiswini (kuze kufike ku-95%). Ukusebenza kwesenzo se-antibacterial kwento ukuvimba ukwakheka kwamaprotheni akha udonga lweseli lwezinto eziphila emzimbeni, okuvimba ukukhula futhi kubangele ukufa kwawo.
Ekuqothulweni kwama-Helicobacter pylori strains anakekela ukuthuthukiswa kwezilonda esiswini kanye nezinye izinhlobo ze-gastritis, inhlanganisela ye-Amoxicillin neClithithycin iyasetshenziswa.
Ukwenza kanjani uClithithycin
I-anti-synthetic antibiotic eqenjini le-macrolide inomphumela we-bacteriostatic, futhi ekugxilweni okuphezulu kukhombisa izakhiwo ze-bactericidal. Umuthi ukhuphule umsebenzi ngokumelene neHelicobacter pylori ngokuqhathaniswa nezinto zochungechunge lwawo. I-Clarithromycin iyakwazi ukudala ukuqoqeka ku-mucosa yesisu ephakeme kune-serum yegazi, okuyichaza njengedakamizwa yokuqala yokukhetha ku-gastroenterology.
Umphumela wokuhlangana
I-bactericum Helicobacter pylori, ebhekele izinhlobo ezihlobene ne-HP zezifo zesisu, ngokushesha iba namandla okulwa nama-anti-antibiotic. Amathuba wokuthi ama-microorganisms abe namandla ezinto ezithile ezisebenzayo ngasikhathi sinye ancipha kaningana.
IClithithycin ehlanganiswe ne-Amoxicillin iyakwazi ukukucindezela ngokushesha ukukhula nokukhiqizwa kwamagciwane ngokwandisa isibuko sokuvezwa nezindlela ezahlukahlukene zokuthonya i-pathogen. Isakhiwo sesikimu sokuqeda kathathu sibandakanya i-proton pump inhibitors - i-Omeprazole noma i-analogues yayo. I-Amoxicillin ingathathelwa indawo yi-metronidazole.
I-Amoxicillin yigciwane elwa ochungechungeni lwepenicillin, oluphawuleka ngethala elikhulu lokwelapha.
Izinkomba zokusetshenziswa ngasikhathi sinye
Inhlanganisela yezidakamizwa isetshenziselwa ukwelapha izifo zokwenza kwasendaweni okuhlukahlukene okubangelwa ama-microorganisms anjalo:
- streptococcus;
- i-salmonella;
- staphylococcus;
- chlamydia
- E. coli.
Womabili la ma-antibhikithikhi achitha ama-microorganisms atholakala ekwakhekeni kwawo, futhi lapho esebenzisana aqinisana.
Ukuhlanganiswa kubekelwe i-pathologies enjalo:
- izifo ze-gastroduodenal zesimo sebhaktiriya: isilonda se-peptic, i-gastritis engapheli, umdlavuza wesibeletho;
- izifo zokuphefumula zamapheshana;
- izilonda ezibangelwa amagciwane esikhunjeni;
- isifo sofuba.
Ukwelapha inhlanganisela kukhonjiswa ikakhulukazi izinhlobo ezingamahlalakhona zezifo ezingalashwa ngomuthi owodwa.
I-Clarithromycin iyi-semisynthetic macrolide antibiotic enomphumela we-bacteriostatic.
Inhlanganisela Clarithromycin-Amoxicillin-Omeprazole yiyona ndlela yokwelashwa engcono kakhulu yokuqedwa kwe-Helicobacter pylori, okuholela ekwelashweni ngamacala angama-85-95%. Umuthi oyinkimbinkimbi i-Pilobact AM osuselwa ezintweni ezi-3 wadalwa ngokuqondile ekwelapheni izifo ezithembela ku-Helicobacter.
Contraindication
I-pair yezidakamizwa ayikwazi ukusetshenziswa ezimweni ezinjalo:
- ukusabela okwenziwa yi-penicillin;
- ukungabekezelelani komuntu ngamunye ukucacisa i-clearithromycin;
- ukwehluleka kakhulu kwezinso noma kwesibindi;
Musa ukunikeza inhlanganisela ku-1st trimester yokukhulelwa. Ngokuqapha, izidakamizwa zisetshenziselwa i-diathesis, i-asthma, isifo sezinso, i-leukemia, ku-trimester yokukhulelwa nangesikhathi sokuzala.
Ungayithatha kanjani i-Amoxicillin neClithithycin
Ngokulashwa okuhlanganisiwe, imithamo ephezulu yazo zombili lezi zidakamizwa isetshenziswa ngokwemiyalelo. Kudlalelwa amaphilisi noma amaphilisi Kuzifo zesibindi nezinso, imithamo iyancishiswa.
Inhlanganisela Clarithromycin-Amoxicillin-Omeprazole yiyona ndlela yokwelashwa engcono kakhulu yokuqedwa kwe-Helicobacter pylori, okuholela ekwelashweni ngamacala angama-85-95%.
I-gastritis
Nge-Helicobacter pylori gastritis, ukwelashwa kukhethwa ngakunye. Zombili lezi zidakamizwa ezibhekele ukunciphisa i-acidity yesisu (i-prostaglandins) kanye nesethi yemithi elwa namagciwane esetshenziswa ihlukile.
Uhlobo lokwelashwa olujwayelekile lubandakanya ukusetshenziswa kwezidakamizwa ezi-3 kwimithamo enjalo:
- I-Clarithromycin - 500 mg;
- Amoxicillin - 1000 mg;
- I-Omeprozole - 20 mg.
Yonke imishanguzo ithathwa kabili ngosuku; inkambo yokwamukelwa ihlala izinsuku eziyi-7.
Kusuka kwesifo sofuba
Ukwelapha okuhlanganayo kukhethwa ngakunye.
Uhlelo lusetshenziswe kaningi:
- I-Amoxicillin - isuka ku-500 iye ku-1000 mg kabili ngosuku;
- I-Clarithromycin - isuka ku-250 mg iye kuma-500 mg izikhathi ezi-2 ngosuku.
I-Amoxicillin ehlangene ne -cacithromycin ihlukaniswa njengomuthi wesibili olwa ne-TB. Ukumelana kwamagciwane kuleli bhangqa kuvamile kunemithi evela eqenjini lokuqala.
Ngezifo zesikhumba
Ukwelashwa kwe-antibiotic okuyi-systemic kwenziwa kwezifo zesikhumba sobunzima obukhulu nobulinganiselayo:
- erysipelas;
- i-furunculosis;
- i-folliculitis;
- impetigo;
- amanxeba athelelekile.
Ezimweni ezinzima, ukwelashwa ngama-antibiotic kungukungezwa kwezindlela zokuhlinzwa.
Imiphumela emibi ye-amoxicillin ne -cacithromycin
Imiphumela emibi ejwayelekile ifaka:
- isicanucanu
- ukuhlanza
- Isiyezi
- imivimbo yesikhumba;
- dysbiosis.
Okungaphawuleki kaningi ukukhula kwe-hypovitaminosis, ukuqina kokuzivikela komzimba. Umphumela wokuvimbela inzalo ngomlomo ungancishiswa.
Umbono wodokotela
Ama-gastroenterologists kanye nodokotela bakwezinye izinto ezikhethekile abazilolayo babheka ukusebenza kwale ndlela yokwelashwa kwezifo ezibangelwa amagciwane. Ngokusho kochwepheshe, umthetho oyinhloko wokwelashwa okusebenzayo ukuhambisana nemiyalelo yezokwelapha kanye nemithamo emisiwe. Awukwazi ukunquma inhlanganisela yama-antibhayorithi ngokunganqikazi.
Ukubuyekezwa kweziguli kwe-Amoxicillin neClithithycin
USergey, oneminyaka engama-48, uVoronezh
Isilonda sami sidalwa ngamagciwane. Babeka inkambo yokwelashwa, kwakwethusa kancane - kunezidakamizwa eziningi, kepha ngaphuza inkambo ngokuphelele. Ngemuva kwenyanga, waphumelela izivivinyo - konke kuhamba kahle.
U-Irina, oneminyaka engama-25, eMoscow
Udokotela unqume imithi elwa nama-2 ekwelapheni i-Helicobacter pylori gastritis. Isimo sesingcono. Akukho miphumela emibi ebonakalayo okwamanje.