Amalungiselelo ekwelashwa kwe-cerebral arteriosulinosis

Enye yezinkinga ezivamile zesifo sikashukela yi-cerebral arteriosulinosis. Lesi sifo sithathwa njengembangela ehamba phambili yokukhubazeka nokufa kwabahlali.

Nge-discepulop encephalopathy, ukuqina kwemisipha ye-lumen, okuthinta ukondleka kwezicubu zobuchopho futhi kube nomthelela ekubonakala kwe-atherosranceotic stenosis. Lokhu kokugcina kuvame ukubangela ukushaywa yi-ischemic kanye nokuwohloka kwemizwa.

Njengoba lesi sifo sinezinkinga eziningi kwisifo sikashukela, ukuphathwa kwe-arteryosulinosis yamakhambi ngezidakamizwa kufanele kube yisibopho. Kepha ngaphambi kokwenza ukwelashwa ngezidakamizwa, kufanele uqonde izimbangela, izimpawu zesifo futhi ubonane nodokotela.

Izici zesifo

I-Atherossteosis iyindlela engapheli yemithambo emikhulu, ebonakala ngokuqongelela kwama-lipids ezindongeni zemithambo yegazi nokukhula kwezicubu ezixhunyiwe kuzo. Imbangela ehamba phambili yalesi sifo ukwehluleka kumetabolism yamafutha. Izici zangaphandle nezangaphakathi zingaholela ekukhuleni kwesifo.

Izizathu ezifanayo zibandakanya ukuguga, lapho amasistimu nezitho ziqala ukusebenza kubi kakhulu ngenxa yezinqubo zokuguga. Ubulili nabo bubamba iqhaza elibalulekile ekutholakaleni kwe-cerebral atherosulinosis. Ngakho-ke, emadodeni, lesi sifo sivela kaningi ngokumelene nesizinda sokuntuleka kwe-estrogen, esibandakanyeka ekuqhekekeni kwe-triglycerides.

I-genetic predisposition iphinde ibalule izinto ezingashintshi ngokubukeka kwamathafa we-atherosclerotic kulwelwesi lwangaphakathi lwemithambo yegazi. Izimbangela zokuguquguquka kwalesi sifo zibandakanya:

1. ukucindezela
2. ukusebenzisa kabi utshwala, ukubhema;
3. hypercholesterolemia;
4. i-metabolic syndrome;
5. umfutho wegazi ophakeme;
6. i-hyperglycemia engapheli;
7. ukungondleki;
8. isisindo ngokweqile;
9. ukugcwala okukhulu kwe-homocysteine ​​egazini;
10. ukwehluleka kwezinso.

Enye i-pathology iba ngokuqhamuka ngemuva kokungasebenzi ngokomzimba, i-hyperfibrinogenemia. Kuyaphawuleka ukuthi, ngokuya ngembangela yengozi, izinhlobo ezinjalo ze-atherosclerosis zihlukaniswa njenge-metabolic, ukuhlobana okuhlobene nobudala, ubuthi, i-allergic kanye nokuvuvukala (syphilis, isifo sofuba).

Uma lesi sifo sivela ngokuqhamuka ngemuva kwe-hypertension ye-arterial, khona-ke ibizwa nge- hyalinosis. Lapho lesi sifo senzeka ngenxa yokuqongelela usawoti we-calcium emithanjeni, khona-ke isiguli sitholakala sine-Mediacalcinosis.

Kunezigaba ezi-4 zokuthuthuka kwe-arteriosulinosis yangaphakathi. Esigabeni sokuqala, ifomu lamabala we-lipid, futhi kwesibili - ama-fibrous plaque.

Isigaba sesithathu sibonisa ukwakheka kwama-atherosselotic plaque kanye nokuqongelela kwenqwaba yama-thrombotic. Esigabeni sokugcina sesi sifo, i-atherocalcinosis iyenzeka, lapho kukhona ukucwaswa kwamachaphaza nokuqothuka kwemithambo.

Ekuqaleni kwentuthuko, i-atherosclerosis ayibonakaliswa. Ngezikhathi ezithile kuphela iziguli zikhononda ngokukhathala okungapheli, ukugxilisa ingqondo okungekuhle, ikhanda elingenangqondo.

Njengoba i-pathology iqhubeka, kuvela izimpawu ezilandelayo:

• tinnitus;
• Isiyezi
• gxuma ekucindezelweni kwegazi;
• uvalo
• ukuqwasha
• ukukhubazeka kwenkumbulo;
• ukungalingani kanye nokuhamba kwezandla;
• ukungasebenzi kahle kwemisebenzi yokubonwayo neyenkulumo.

Ezimweni ezisezingeni eliphakeme, kunokukhubazeka kothandekayo womzimba, ukuqina kobuso, ukuqina kwemilenze. Futhi, i-atherosclerosis yesigaba 3-4 ibonakala njengophawu olufana nokudideka. Imvamisa, iziguli zikhononda ngokuntuleka okuphelele kokusebenza, futhi kwezinye iziguli, kwenzeka ukonakala kobuntu obuthile.

Ngaphambi kokuthatha noma imiphi imishanguzo ye-atherosulinosis yemikhumbi yokuqothula, kuyadingeka ukuxilongwa ngokuphelele. Izifundo zaselaborathri zifaka ukuhlolwa kwegazi elenziwa ngemvelo kanye ne-biochemical.

Indlela enhle yokuthola i-atherosclerosis yi-MRI. I-Ultrasound, i-angiography ne-transcranial dopplerography isebenza ngokufanayo.

Imigomo ejwayelekile yokwelashwa

Ukwelapha i-arteryosulinosis yamakhorali kumele impela kube okuphelele futhi kube nezindlela ezinobuphawu, ubuchwepheshe be-pathogenetic kanye nokulungisa. Kepha ngaphambi kokuthatha imishanguzo, odokotela beluleka iziguli ukuthi zikubukeze ukudla kwazo.

Ukwelashwa kokudla kuzokwenza ukwelashwa kwezidakamizwa kuphumelele futhi kunciphise ukuqhubeka kwesifo. Umgomo oyinhloko wokudla kokudla emzimbeni we-cerealsteosis ukwenqatshwa kokudla okunamafutha okuvela emvelweni wezilwane, ukusetshenziswa okulinganiselwe kasawoti nanoma yikuphi ukudla okulimazayo (ukudla okusheshayo, amasoseji, ukudla okulula).

Ngama-pathologies we-vascular, odokotela batusa ukubheka umfutho wegazi njalo, ukuqapha amazinga eglucose ne-cholesterol egazini. Ngokubalulekile ukwenqatshwa kwemlutha, ukuguqulwa kwesisindo, inqubo yansuku zonke. Akumele sikhohlwe ngokuzivocavoca okulinganiselayo futhi sigweme izimo ezicindezelayo.

Uma i-atherosclerosis yemithambo ye-cerebral itholakala, ukwelashwa kwezidakamizwa kukuvumela ukuthi uthole imiphumela elandelayo elandelayo:

1. umfutho wegazi;
2. ukwehla kwe-hypoxia yobuchopho;
3. ukulungiswa kwe-lipid metabolism;
4. ukuvuselelwa kwe-lumen ye-vascular.

Ukwelapha i-atherossteosis yangaphakathi kuhlanganisa ukusebenzisa izidakamizwa ezingamaqembu ehlukene wezidakamizwa.

Izitatimende, ama-bile acid sequestrants, ama-antiplatelet agents, i-Vitamin PP, i-fibrate, izidakamizwa ze-anticholesterol nezidakamizwa ezenza ukuthi umfutho wegazi zisetshenziswe ngokwejwayelekile.

Izimo

Le mishanguzo ibhekwa njengesisekelo sokwelashwa kwe-atherossteosis, njengoba isusa imbangela yokubonakala kwayo - i-hypercholesterolemia.

Umphumela wokwelapha wama-statins ukuvimbela ukufihlwa kwe-enzyme ebhakwe ebhekene nokukhiqizwa kwe-cholesterol, ukwandisa ukuqoqwa kwe-lipoprotein “ewusizo” ephezulu, ukwenza ngokweqile i-lipid metabolism, i-resorb atherosulinotic plaque, futhi kuqinise futhi kuphilise imithambo yegazi.

Amaphilisi amahle kakhulu we-cerebral arteriossteosis avela esigabeni sama-statins amasha esizukulwane:

Naphezu kweqiniso lokuthi ama-statin anomphumela ophansi we-lipid-okwehlisa ukwelashwa, anemiphumela emibi eminingana. Okuvame kakhulu kuzo yi-pathologies yezicubu zomzimba, ukungezwani komzimba, ukungasebenzi kahle kohlelo lwezinzwa oluphakathi kanye nokusebenza kokuphazamiseka kohlelo lokugaya ukudla.

Ukuxhumana kokuthathwa kokuthatha ama-statins - isifo sesibindi, izingane ezingaphansi kweminyaka engu-8 ubudala, ukungabekezeleli komuntu ngamunye.

Imithi ayenqatshelwe ukusebenzisa uma kukhulelwa, ukuphuma kwe-lactation nokuqukethwe okuphezulu kwama-transaminases egazini.

Izicucu

I-Fibroic acid derivatives iyiqembu lesibili eliphumelela kakhulu lezidakamizwa elenzelela i-lipid metabolism. Banciphisa inani lamafutha ayingozi emzimbeni ngo-50%, bandisa izinkomba ze-cholesterol enhle egazini. Umphumela wokwelapha utholakala ngokwandisa ukugcwala kwama-enzymes akhethekile asebenzisa ukususwa kwama-lipoprotein aphansi womzimba emzimbeni nge-bile.

Emaphepheni atherossteotic, ama-fibrate anqunywa kanye nama-statins, ikakhulukazi lapho i-hypercholesterolemia ihambisana ne-triglyceridemia. Kodwa ngokungabekezeleli ama-enzyme wesibindi we-enzyme, i-fibroic acid derivatives ingathathwa ngokuhlukile.

Umuthi osebenzayo we-cerebral arteriosulinosis ovela esigabeni sama-fibrate yiFenofibrate. Imithamo yomuthi yansuku zonke ingaqala ku-140 iye ku-400 mg.

Ama-Derivatives we-fibroic acid, njengama-statins, athathwa ngezifundo - kusuka ezinyangeni ezi-3. Amathebhulethi adakwa kuze kube izikhathi ezi-2 ngosuku.

Izidakamizwa ezidumile ezivela esigabeni sama-fibrate:

• Bezafibrat. Ungathatha kufika ku-0,3 g womkhiqizo ngesikhathi.
• Clofibrate. Inomphumela ohlelekile - ivimba i-enzyme yesibindi, iphule amafutha, inciphise ukubukeka kwegazi nokuhlushwa kwe-uric acid. Ungaphuza amaphilisi afinyelela kwayi-9 ngosuku, amaphilisi ayi-2-3 ngasikhathi.
• Gemfibrozil. Umuthi uthathwa 1 (900 mg) noma 2 (600 mg) kanye ngosuku ngaphambi kokudla.
• I-Lipanor Umthamo ezinsukwini zokuqala ezingama-90 zokwelashwa ngu-100 mg ngosuku, khona-ke ungakhushulelwa ku-200 mg. Uma kunesidingo, isidakamizwa sisetshenziswa iminyaka eminingana.
• I-Ciprofibrate. Ihluka kwamanye ama-fibrate esenzweni eside, okunciphisa isikhathi sokwelashwa kanye nenombolo yemithamo yomuthi. Amaviki okuqala ayi-8 ukuya ku-12, umuthi unqunywe ngesimo se-monotherapy, khona-ke ukusetshenziswa kwawo kuhlangene nezinye izidakamizwa ezilwa ne-atherossteotic.

Ukubuyekezwa kwabantu abaningi abaphethwe yi-cypheralsteosis kuqinisekisa ukuthi ngamaphesenti angama-90, ama-fibrate abekezelelwa kahle. Ngakho-ke, ukusabela okungekuhle (komzimba, isicanucanu, ukuphakama kokugaya ukudla, ukonakala kwe-potency) akuvamile kakhulu. Kodwa-ke, esimweni sokubambisana kokubambisana kwe-fibroic acid ngama-statins, ukusebenza kwesibindi kuvame ukwanda.

Noma iyiphi i-fibrate contraindicated ku-renal noma i-hepatic insuffence, ukukhulelwa kanye ne-lactation.

Izidakamizwa ezinjalo azinqunyelwe ukungasebenzi kahle kofuzo ku-carbohydrate metabolism, futhi izingane nentsha nazo zenqabele ukuzithatha.

Ama-ejenti we-antiplatelet nabahleli bezikhathi

Ama-antiplatelet agents angama-ejenti anciphisa amandla okuhlanganisa ama-enzymes abunjiwe, akhulisa ukuphuma kwegazi futhi avimbele ukwakheka kwezigaxa zegazi. Isidakamizwa esidume kakhulu esiliqembu lesi sidakamizwa ngu-Aspirin.

Izinzuzo zomuthi yizindleko eziphansi nezenzo ezisheshayo. Kodwa-ke, kufanele wazi ukuthi i-acetylsalicylic acid iyacasukisa i-mucosa yesisu, ngakho-ke i-contraindicated ku-gastritis kanye nesilonda.

Amanye ama-antiplatelet agents owaziwayo, ukusetshenziswa kwawo okusiza ukugwema ukungenelela kokuhlinzwa kwe-thrombosis, yi-Thrombo ACC, Cardiomagnyl, Clopidogrel.

Ama-sequelators we-Bile acid elinye iqembu lezidakamizwa elinqunyelwe i-cerebral arteriosulinosis. Ama-ejenti enza ngokomgomo okhethekile wokushintshana kwama-ion. Imithi isusa amafutha e-acid emzimbeni, kufaka ne-cholesterol embi.

Uma kuqhathaniswa nalezi zidakamizwa ezingenhla, ama-sequestrants anokusebenza okuphakathi kwezidakamizwa. Kepha banezinzuzo - intengo efanelekile kanye nobungozi obuncane bokuphendula okungalungile.

Abalandela iziqu abadumile:

1. Isilinganiso. Ukumiswa kuthathwa ngomlomo ku-dosage ka-4 g ngesikhathi ngaphambi kokudla. Isikhathi sokwelashwa sinqunywa ngudokotela. Imiphumela emibi engaba khona wukuphulwa kokugaya, ukwehla kwesilinganiso samavithamini ancibilikiswa emzimbeni emzimbeni.
2. Colestipol noma Colestid. Kutholakala ngesimo samathebulethi (5 g) ne-powder (1 g). Esigabeni sokuqala sokwelashwa, isilinganiso esisodwa somuthi singama-5 amagremu, kamuva, inani lingakhuphuka liye kumagremu angama-30.
3. I-Questran iyatholakala ngefomu le-powder. Umthamo wansuku zonke wezingane yi-1 sachet, kubantu abadala - imishanguzo eyi-6. Ngesikhathi sokulashwa nomuthi, kunconywa ukuphuza uketshezi oluningi.

Ezinye izidakamizwa ezisebenzayo

IVitamin PP idlala indima ebalulekile ekwelapheni i-atherossteosis. Into inezakhiwo eziningi ezinhle. Inomphumela we-hypotensive, anticholesterol, vasodilator ne-fibrinolytic.

Uma kwenzeka ukuthi i-cerebral arteriossteosis, i-nicotinic acid isebenze i-lipoproteidlipases futhi isuse ama-acid wamahhala, inciphisa ukugcwala kwe-TG.

Imikhiqizo esekwe kuVitamin PP iyatholakala ngezindlela ezahlukene zemithamo futhi iphuzwa ngemuva kokudla. Umthamo wansuku zonke onconywayo ngu-3-5 amagremu.

I-drug overdose esekwe ku-nicotinic acid ingadala ukuvutha okukhulu. Contraindication - urolithiasis, ukwehluleka kwesibindi, ukungasebenzi kahle kwendlela yokugaya ukudla.

Futhi, nge-atherossteosis, ama-vasodilators anqunyelwe. Banwebisa ukukhanyiswa kwemithambo yobuchopho futhi baqhube inkambo yesifo, ethuthukisa ukuhamba kwegazi futhi ikhuphule amandla e-neural energy metabolism.

Izidakamizwa ze-vasodilator ezisebenzayo:

• I-Cinnarizine;
• INorvask
• INimodipine;
• ILacipil;
• Adalat nabanye.

Ngokwehlukana, kufanelekile ukuqaphela umuthi obizwa nge-Detralex. Lona umuthi wokuqamba ohlanza ngokushesha futhi uthambise imithambo yegazi yobuchopho. Kepha kaningi, iDetralex ilashwa ngokuqothula i-atherosclerosis, ngoba isusa ukuvuvukala, usizi nobuhlungu emilenzeni.

Amavithamini kanye namaminerali ayingxenye ebalulekile yokwelashwa okuyinkimbinkimbi yokuqedwa kwamalungu emithambo enama-cholesterol plaque. Izinto ezilusizo ezidingekayo kuma-pathologies we-vascular: amavithamini PP, C, B kanye nezinto zokulandela - i-silicon, potassium, selenium.

Njengoba i-atherosulinosis imvamisa ihambisana nomfutho wegazi ophakeme, izidakamizwa ze-hypotensive zifakwa ekwelashweni okuyinkimbinkimbi kwesifo sikashukela. I-Indapamide, i-Captopril, iHydrochlorothiazide, iNifedipine neCarvedilol banomphumela omuhle wokwelapha. Futhi ngezigaba ezithuthukile ze-atherossteosis, isiguli singanikwa amadonsi ngezidakamizwa ezinamandla ukuhlanza futhi kunciphise igazi.

Ukuqeda izimpawu ezingemnandi zama-pathologies we-vascular, ukwelashwa okubonakalayo kuyenziwa. Imvamisa, udokotela ubeka imishanguzo yokudambisa izidakamizwa, izidakamizwa ze-psychotropic, analgesics, tranquilizer.

Njengendlela yokwelapha edjunct engcupheni eyengeziwe yokuqhekeka kwegazi, ukugcoba okusekwe ezitshalweni zokwelapha kungasetshenziswa. Futhi uma kufiswa, iziguli zinganezela ukwelashwa okuphelele ngamakhambi esintu.

Nge-atherosclerosis yobuchopho, amakhambi anjenge-periwinkle, i-lemon balm, i-valerian, i-dill, i-mint, i-borax, i-melilot, i-meadowsweet, usizo lwe-clover. Okokukhuthaza i-microcirculation, ukuqedwa kwe-vasasm spasm kanye nokuncipha kwegazi, kwenziwa amalungiselelo aqukethe i-ginko-biloba ekhishwe -Tanakan, Ginko Fort neBilobil.

Ukuthi i-brain atherosclerosis yelashwa kanjani ichazwa kuvidiyo kule ngxenye.