Ukulungiswa kwe-enzyme ye-Penzital kwenziwa ngendlela yamathebulethi ehlanganisiwe, isithako esikhulu esisebenzayo yi-pancreatin enomsebenzi we-enzymatic we-lipase, amylase ne-proteinase. Ngaphezu kwalokho, ukwakheka komkhiqizo kuqukethe izinto ezisizayo, kufaka phakathi i-lactose monohydrate, okumele icatshangwe uma le ngxenye ingabekezeleli.
Asiza kanjani amaphilisi? Umuthi uyanconywa kwiziguli ezingenele ukusebenza kwe-exocrine pancreatic function, ukwenza ukuthi ukusebenza kwesistimu yokugaya ukudla kube yikujwayelekile, zivame ukwehlisa amafutha namaprotheni abe izinhlayiya ezincane.
Ngenxa yokuba khona kwegobolondo elikhethekile, ithebhulethi iyoncibilika kuphela emathunjini amancane, bese kuba nomphumela owelapha emzimbeni. Umsebenzi ophakeme wesidakamizwa ubonwa imizuzu engama-45 ngemuva kokuthatha umuthi. Intengo ephakathi yamaphilisi okupakisha ama-ruble angama-60.
Imiyalo yokusebenzisa amaphilisi
Umuthi uhloselwe ukusetshenziswa kwangaphakathi uma kwenzeka ukungapheleli kwe-pocrreatic pancreatic okubangelwa izifo zalesi sitho, kufaka phakathi i-pancreatitis engapheli. Kubekelwe ukudambisa lesi simo ngemuva kokulashwa ngokuhlinzwa ku-gland, inqubo yokugaya ukudla ngemuva kwe-chemotherapy yamathumbu anomdlavuza ezingxenyeni zohlelo lwesisu.
Izinkomba zokusebenzisa i-Penzital yi-cystic fibrosis, amaphutha ekudleni okunempilo, ukusetshenziswa kabi kokudla okusheshayo, ukudla ngokweqile, umsebenzi wokuhlafunisisa okhubazekile (lapho izingcezu ezinkulu kakhulu zokudla zingena esiswini). Amathebulethi kufanele adakwe ngaphambi kwe-x-ray, i-ultrasound of the patity esiswini.
Imiyalo esetshenziswayo ibuye ikhombise ukungqubuzana nomuthi, okuthi phakathi kwawo inqubo yokuvuvukala i-pancreas (i-pancreatitis e-acute, esebenzayo kanye neyeqile). Okunye ukweqa umthetho ukungabekezelelani kwezinto ezisebenzayo.
Thatha umuthi ngesikhathi sokudla noma ngokushesha ngemuva kokudla, udinga ukuphuza amaphilisi ayi-1-2:
- ginya lonke;
- ungahlafunisi;
- phuza ingilazi yamanzi.
Kunconywa abantu abadala izikhathi ezi-3 ngosuku, ezinganeni ezingaphansi kweminyaka engu-12, umthamo unqunywa ngokuhlukile ngokuya ngesisindo somzimba.
Isikhathi sesifundo sisuka ezinsukwini ezimbalwa kuya ezinyangeni ezimbalwa, udokotela uthatha isikhathi sokulashwa, kusukela ekuxilongeni nasezimpawu zomzimba wesiguli. Inzuzo engenakuphikwa yemithi ukuthi ayiyimilutha, asikho isifo sokuhoxa ngemuva kokuphothula ukwelashwa.
Ekhulelwe, ukuphepha kokusetshenziswa kwomuthi akukafundwa ngokugcwele, ngenxa yalesi sizathu ukwelashwa kuvunyelwe inqobo nje uma inzuzo okuhlosiwe iphakeme izikhathi eziningana kunobungozi obukhona enganeni.
Ngokuqondene nesikhathi sokuncelisa, i-Penzital ivunyelwe, kepha uzodinga ukubheka ukusabela kwengane kulo muthi, ukusabela okwenziwa yi-allergic, ukuqubuka kwesikhumba akuhlanganisiwe.
Ezimweni ezinjalo, kufanele ngokushesha uyeke ukuthatha amaphilisi.
Ukuphendula okungafani, i-overdose, ukuxhumana
I-Penzital ivame ukubekezelelwa kahle yiziguli ezine-pancreatitis engapheli, ngokuzwela ngokweqile komuntu ngamunye kulo muthi, ukuphazamiseka okuvela ezinhlotsheni nasezinhlelweni ezahlukahlukene kuyabonakala.
Ukusuka emgodini wokugaya ukudla kusho ukuqunjelwa, usizi esiswini, i-stomatitis, ukucunula kwe-integument endaweni yendawo yepheriya, i-flatulence, isicanucanu, nokuhlanza. Kwenzeka ukuthi umzimba uphendule ezibhebheni ngokushintsha ukuhlolwa komchamo, uveze i-hyperuricemia, hyperuricosuria.
Ezinye iziguli zinezichoko, amakhasi, imivimbo yesikhumba, ubomvu, nokulunywa kanzima. Ukubonakaliswa okunjalo akubeki usongo empilweni, akuyona ingozi, futhi kudlula ngokushesha ngemuva kokwehlisa umthamo noma ukuyeka ukwelashwa.
Uma isiguli esine-cystic fibrosis sithatha kakhulu, angaqala ukukhulisa i-fibrous colonopathy kukholoni. Uma kwenzeka kusetshenziswa ngokweqile ingozi, isiguli sikhula:
- ukuqunjelwa
- ukuhlanza
- isicanucanu
Izimpawu ezinjalo zidinga ukwelashwa okubonakalayo.
Ukulungiselela i-enzyme akufanele kubekelwe iziguli kanye nokulungiswa kwensimbi; ngaphansi kwethonya lamathebulethi, ukunqandwa kokuvinjwa kanye nokufakwa kwe-iron okulimazayo kuyabonakala. Kungcono ukungasebenzisi umuthi ngama-sorbents, lokhu kunciphisa umphumela wokwelapha wePenzital.
Yini enye okudingeka uyazi
Imithamo yomuthi enkambeni engapheli ye-pancreatitis ne-cystic fibrosis kufanele ibalwe isiguli esithile esithile, gwema ukwedlula okuthe xaxa ukukhipha ukukhula kwe-fibrous colonopathy.
Iminyaka eminingi yesipiliyoni ekusebenziseni kwamathebhulethi ezinganeni zasenkulisa ilinganiselwe noma ayikho ngokuphelele, ngenxa yalesi sizathu, ukubonisana nodokotela kuyadingeka ngaphambi kokwelashwa. Ngesikhathi sokuvivinywa komtholampilo, kwakungekho mphumela we-mutagenic, teratogenic kanye ne-embryotic enganeni, kepha abesifazane abakhulelwe kufanele basabe ngokuqaphela ngoba imizimba yabo iyakwazi ukuphendula ekwelashweni ngendlela ebingalindeleki kakhulu.
Ngokusho kokubuyekezwa, amaphilisi awakuthinti kabi ukusebenza kwesistimu yezinzwa ephakathi, ayenqatshelwe ukushayela izimoto ngesikhathi sokwelashwa, ukuphatha izindlela eziyinkimbinkimbi ezidinga ukunakwa okwengeziwe.
Umuthi ungathengwa ekhemisi ngaphandle kwemiyalelo evela kudokotela, okuhlanganiswayo kufanele kungagcinwa kude nezingane ezincane, kufanele kube yindawo eyomile futhi epholile.
Impilo yeshelf iyakhonjiswa epakethe, imvamisa kuyiminyaka emibili kusukela ngosuku okwenziwe ngalo amaphilisi. Kwenqatshelwe ukuhlanganisa utshwala ne-penzital.
Analogs of the drug Penzital
Izithasiselo ezithandwayo zePenzital yizibhebhe i-Creon, Festal, Mezim, Panzinorm nePancreatin. Kuzo, inani lezinto eziphambili ezisebenzayo lihlukile, ngenxa yalesi sizathu akufanelekile ukufaka esikhundleni somuthi obekwe udokotela ngokwakho. Uzodinga kuqala ukucacisa umthamo owodwa ophakanyisiwe futhi owenziwa nsuku zonke. Yikuphi okungcono iPenzital noma Pancreatin? Akunakwenzeka ukuphendula ngokungalingani, ngoba izidakamizwa zinokuhluka okuhlukile kwezinto ezisebenzayo.
Kaningi, esikhundleni se-Penzital, odokotela banquma i-Mezim, izinto ezisebenzayo zomuthi zisiza ngokushesha ukumisa ukuphazamiseka okuhlukahlukene okubangelwa ama-enymes anganele we-pancreatic, futhi kunciphise umuntu wezimpawu ezingemnandi zenkambo engapheli ye-pancreatitis. Ingxenye ye-trypsin iyabulala, ivimbela imfihlo yokuphuza ujusi we-pancreatic.
Incazelo kaMezim ithi izosiza ukuqeda ukugaya ukudla nokuqhakaza okubangelwa ukudla ukudla okuningi okungahambelani. Isibhebhe kufanele siphuzwe sonke, sihlanzwe ngamanzi ahlanzekile. Kwenqatshelwe ukugaya amaphilisi, ama-enzyme ancibilika endaweni enolaka esiswini, anciphise ukusebenza kwezokwelapha.
Uhlelo lokwamukelwa okujwayelekile:
- abantu abadala badinga ukuthatha amaphilisi ama-1-2 izikhathi ezi-1-3 ngosuku;
- izingane ezineminyaka eyi-12-18 ubudala zinqunywe i-20,000 IU yento ngale kilogremu yesisindo;
- Izingane ezingaphansi kweminyaka eyi-12 kufanele zinikezwe i-1,500 IU ngekhilogremu yesisindo.
Isicelo sesifo se-pancreatitis esingamahlalakhona singaba sodwa, lapho kunesidingo sokuqeda ukuphulwa kwesikhashana kwenqubo yokugaya ukudla, noma isikhathi eside futhi kuthathe izinyanga ezimbalwa.
Umuthi i-Mezim wenqatshelwe ngokungabekezeleli komuntu ngamunye ezingxenyeni zomuthi, umuzwa okweqile womzimba. Kuyadingeka ukunaka ukuthi amaphilisi awakwazi ukudliwa enkambeni yokuvuvukala kumakhankethi, ngaphandle kwalokho lesi sifo sizodlula.
Ngesikhathi sokulashwa, imiphumela emibi kungenzeka ngesimo sokuhlaselwa isicanucanu, ukungahambi kahle emathunjini, komzimba, isihlalo sangaphansi kanye nobuhlungu emgodini wesisu. Ukusetshenziswa isikhathi eside kwesidakamizwa kuvusa ukwanda kwezinga le-uric acid, ukuthuthukiswa kwe-hyperuricemia yesifo.
Uma isiguli sithatha uMezim isikhathi eside kanye nemithi, ukuphuma kwe-iron ngamathumbu kuyancipha, i-anemia, i-pallor yesikhumba, ubuthakathaka bemisipha, kanye nokukhubazeka okungasebenzi.Uma uMezima esetshenziswa ngokuhambisana namalungiselelo e-antacid aqukethe i-calcium ne-magnesium, ukusebenza kwe-ejenti ye-enzyme kuzoncipha.
Izindlela zokwelapha i-pancreatitis kuxoxwa ngazo kule vidiyo kulesi sihloko.
