Abaningi bezwe ngalokho uDokotela Myasnikov atshela ngakho ngeMetformin, ukuchaza kahle ukuthi ziyini izinzuzo zalo muthi, nokuthi unaziphi izici ezihlukile.
Enye yezimpawu eziphambili zalesi sidakamizwa ukuthi ikulwela ngenkuthalo ukunganakwa komzimba ku-glucose. Le nkinga ngqo eyenzeka ezigulini ezinesifo sikashukela sohlobo 2, futhi, ngenxa yalokho, ezinezinkinga zokukhuluphala ngokweqile. Sikhuluma ngemithi efana neSiofor noma iGlucofage.
Ngingathanda futhi ukuqaphela ukuthi inkolelo-mbono kaMyasnikov isuselwa kumaqiniso athile kanye nemiphumela yocwaningo. Ngakho-ke, kufaka phakathi ukuthola umphumela othize kanye nokufinyelela izinhloso ezisethwe ekuqaleni.
Isibonelo, okunye kokuhlola okunjalo kwakuwucwaningo olwabonisa ukuthi iMetformin ithinta kahle ukuqiniswa kwemithambo yegazi. Kulokhu kuhlangana, ubungozi bokuqalwa kwe-atherosclerosis buyancipha. Futhi, iziguli eziphuza lo muthi zingahle zingakhathazeki ngokuthuthukiswa kwemivimbo yokuqala noma isifo senhliziyo.
Ngaphezu kwalokho, kuye kwafakazelwa ukuthi izidakamizwa ezichazwe ngenhla zisiza ukunciphisa ingozi yokuthuthukisa i-oncology. Njengoba wazi, lokhu kuhlangana kuvame kakhulu kwabanesifo sikashukela. Vele, ukuze uzuze umphumela onjalo, udinga ukuthatha umuthi isikhathi esithile, futhi ikakhulukazi njalo kukho konke ukwelashwa.
Yebo, kunjalo, kufanele kuphawulwe ukuthi leli ngelinye lamathuluzi ambalwa asiza isiguli ukunciphisa isisindo sabo ngempumelelo. Ngenxa yalokhu, ingabhekelwa ezigulini ezihlushwa isisindo somzimba ngokweqile, noma ushukela wazo uvamile.
Enye inzuzo ye-Metformin iqiniso lokuthi ngokusetshenziswa isikhathi eside, namanje alisehli izinga le-glucose egazini elingaphansi kuka-1.5 mmol / L. Lokhu iqiniso elibalulekile, ngoba kulokhu kungenzeka ukuthi kusetshenziswe ngisho nakubantu abangahlushwa isifo sikashukela, kodwa abanezinkinga zokukhuluphala ngokweqile.
Futhi, umuthi ulwa nenye inkinga ebalulekile evame ukuhambisana nesifo sikashukela sabesifazane. Okungukuthi, sikhuluma ngokuzala. Ukusetshenziswa njalo kwesidakamizwa kusiza ukubuyisela i-ovulation.
Ukusetshenziswa kwesidakamizwa iMetformin
I-Metformin inconyelwe ukusetshenziselwa ukudla okune-khalori ephansi.
Ngaphezu kwakho konke ukuxilonga okuchazwe ngenhla, kunezinye izimo lapho kunconywa ukusetshenziswa kwalo muthi.
Ngaphambi kokusebenzisa umuthi ukwelashwa uwedwa, kunconywa ukuthi uvakashele udokotela ozokuthola izeluleko nezincomo eziphathelene nokwelashwa nge-Metformin.
Ngakho-ke ukusetshenziswa kweMetformin kuzoba nesizathu esifanele uma isiguli sinokuphulwa okulandelayo:
- Ukulimala kwesibindi esinamafutha
- Isifo se-Metabolic.
- I-Polycystic.
Ngokuqondene ne-contraindication, lapha okuningi kuncike ezicini ezithile zomzimba wesiguli esithile. Ake sithi kunezimo lapho, ngemuva kokusebenzisa umuthi isikhathi eside, isiguli siqala ukuba nokulinganisela kwe-acid emzimbeni. Ngakho-ke, odokotela batusa ukusebenzisa amaphilisi anjalo ngokuqapha uma kukhona umsebenzi wezinso ophazamisekile.
Kunconywa futhi ukuthi uhlaziye amazinga we-creatinine ngaphambi kokuqala ukwelashwa. Yabela kuphela uma ingaphezulu kwe-130 mmol-l emadodeni futhi ngaphezulu kwe-150 mmol-l kwabesifazane.
Kuyiqiniso, imibono yabo bonke odokotela incishiswa ukuthi iMetformin ilwa noshukela kahle kakhulu, futhi ivikela nomzimba emiphumeleni eminingana yalokhu kugula.
Kepha noma kunjalo, uDkt Myasnikov nabanye ochwepheshe bomhlaba banesiqiniseko sokuthi akufanele kubhekiswe kulabo abaguli abanezinkinga notshwala, okuwukuthi busebenzisa ngokweqile nalabo abahlushwa ukuhluleka kwesibindi.
Izincomo ezibalulekile zikaDkt. Myasnikov
Ekhuluma ngqo ngenqubo kaDkt Myasnikov, uncoma ukusebenzisa lezi zimali nezinye izidakamizwa.
Lezi izidakamizwa ezihlobene ne-sulfonylureas. Ake sithi kungaba yiManinil noma iGliburide. Ngokubambisana, la ma-ejenti asiza ukuthuthukisa umsebenzi we-insulin secretion emzimbeni. Kuliqiniso, kunezithiyo ezithile kulolu hlobo lokwelashwa. Owokuqala wabo kubhekwa ukuthi ngokuhlangana lezi zidakamizwa zombili zinganciphisa ngokushesha amazinga kashukela, ngenxa yalokho isiguli singalahlekelwa nawukungazi. Kungakho, ngaphambi kokuqala ukwelashwa ngemithi emibili, kufanele wenze ukuhlolwa okuphelele komzimba wesiguli futhi uthole ukuthi yimuphi umuthi wemithi ofanele kakhulu kuye.
Elinye iqembu lezidakamizwa elisebenza kakhulu ekuhlanganiseni ne-metformin yiPreandin neStarlix. Banomphumela ofanayo nezidakamizwa zangaphambilini, kuphela zinomphumela emzimbeni ngendlela ehlukile kancane. Njengasesimweni esedlule, ungabona futhi ukwanda okuncane kwesisindo kanye nokwehla ngokweqile kwe-glucose yegazi.
Futhi, umuntu akufanele akhohlwe ukuthi iMetformin 850 ikhishwe kabi emzimbeni womuntu, ngakho-ke kungcono ukungayisebenzisi kubantu abanezinkinga zezinso.
Imetformin ingahlanganiswa yini?
Ngaphezu kwayo yonke imishanguzo echazwe ngenhla, kukhona ezinye izidakamizwa uDkt Myasnikov ezincoma ukuthatha ne-metformn. Lolu hlu kufanele lubandakanye i-Avandia, ukukhiqizwa kwasekhaya nama-Aktos. Kuliqiniso, lapho uthatha le mishanguzo, kufanele ukhumbule ukuthi inezinhlobo zemiphumela esezingeni eliphakeme kakhulu.
Isibonelo, muva nje, odokotela batusa iziguli zabo ukuthi zisebenzise i-resulin, kepha ucwaningo oluningi selukhombisile ukuthi linomphumela omubi kakhulu esibindini. NaseYurophu, u-Avandia no-Aktos bavinjelwe. Odokotela abavela emazweni e-Europe ahlukahlukene baphikisana ngamabomu ukuthi umphumela omubi onikezwa yile mithi uyingozi kakhulu kunomphumela omuhle osetshenziswa ngabo.
Yize iMelika isaqhubeka nokusebenzisa imishanguzo echazwe ngenhla. Kumele kukhunjulwe iqiniso elilodwa lokuthi kwakungamaMelika lapho iminyaka eminingi yenqaba ukusebenzisa iMetformin, yize yayisetshenziswa kabanzi kuwo wonke amanye amazwe. Ngemuva kwezifundo eziningi, ukusebenza kwayo kufakazelwe, futhi amathuba ezinkinga ancishiswa kancane.
Ekhuluma ngqo nge-Aktos noma i-Avandia, kufanele kukhunjulwe ukuthi kuholela ekwakhiweni kwezifo zenhliziyo eziningi, futhi kungadala ukukhula kwesimila somdlavuza. Ngakho-ke, ezweni lethu, odokotela abanolwazi asiphuthumi ukuba banikeze le mithi ezigulini zabo.
Kufakwa izinhlelo ezahlukahlukene, ezixoxa ngempumelelo yomuthi othile. Ngenye yalokhu kudutshulwa, uDkt Myasnikov ukuqinisekisile ubungozi bale mithi.
Iseluleko sikaDkt Myasnikov ngokusetshenziswa kweMetformin
Akunzima ukuthola amavidiyo ku-Intanethi lapho udokotela osechaziwe akhuluma khona ngokuthi ungayithuthukisa kanjani kahle inhlalakahle yakho ngosizo lwemithi ekhethwe kahle.
Uma sikhuluma ngento ebaluleke kakhulu eyelulekwa nguDkt. Myasnikov, kubalulekile ukuqaphela ukuthi uyaqiniseka ukuthi inhlanganisela eyiyo yezidakamizwa ezinciphisa ushukela ingasiza ekunqobeni hhayi kuphela izimpawu zesifo sikashukela uqobo, kepha futhi ibhekane nokugula okuningi okuvela eceleni.
Uma sikhuluma ngalezo ziguli ezinoshukela wazo zigxuma kakhulu ngemuva kokudla ngakunye, lapho-ke zingcono ukusebenzisa imishanguzo efana neGlucobay noma iGlucofage. Ivimbela ngempumelelo amanye ama-enzyme ohlelweni lokugaya komuntu, ngaleyo ndlela ivuselela inqubo yokuguqula ama-polysaccharides abe yifomu oyifunayo. Kuliqiniso, kunemiphumela emibi ethile, okungukuthi, ukuqhakaza okukhulu noma isifo sohudo kuyabonakala.
Kunelinye iphilisi, elihlongozwayo futhi kubo bonke labo abanezinkinga ezifanayo. Kuliqiniso, kulokhu, ukuvimba kwenzeka ngezinga lamanyikwe. Lokhu yi-Xenical, ngaphezu kwalokho, kuvimbela ukumuncwa ngokushesha kwamanoni, ngakho-ke isiguli sinethuba lokwehla isisindo futhi senze i-cholesterol ejwayelekile ibe yejwayelekile. Kepha kulokhu, futhi udinga ukwazi ngemiphumela emibi engaba khona, yile:
- isilonda sesisu;
- ukuphazamiseka kwendlela yokugaya;
- ukuhlanza
- isicanucanu
Ngakho-ke, ukwelashwa kwenziwa kangcono kakhulu ngaphansi kokuqashwa kukadokotela.
Muva nje, kuye kwavela ezinye izidakamizwa ezithinta ama-pancreas ngendlela emnene futhi zinenqwaba yemiphumela emibi.
Abesifazane abaneminyaka engama-40 bavame ukuba nentshisekelo embuzweni wokuthi bangaluhlula kanjani ushukela ophakeme noma ukugxuma kwalo okungazelelwe futhi ngasikhathi sinye benze ngokwejwayelekile isisindo sabo. Kulokhu, udokotela uncoma umuthi onjengeBaeta.
Kwividiyo ekulesi sihloko, uDkt Myasnikov ukhuluma ngoMetformin.