I-Amaryl isidakamizwa esisiza ukunciphisa ushukela wegazi.
Ukuphuza kwayo kuqala lapho ukuntuleka kwe-insulin kungasenakunxeshezelwa ezinye izindlela - ukuvivinya umzimba, ukudla, amakhambi abantu, kepha asikho isidingo sokuphatha i-insulin emsulwa.
Ukuthatha lesi sidakamizwa kunomthelela omuhle esimweni sabantu abanesifo sikashukela, esingathuthukisa kakhulu impilo yabo.
Ngakho-ke, i-Amaryl, ama-analogues ayo akhiqizwa yizinkampani ezahlukahlukene zemithi, isetshenziswa kabanzi ekwelapheni imiphumela yokuntuleka kwe-insulin emzimbeni.
Izinkomba nezinto ezisebenzayo
I-Amaryl nezimpawu zayo kuboniswa isifo sikashukela sohlobo II. Isithako esisebenzayo somuthi yi-glimepiride.
Lesi sidakamizwa sesizukulwane sesithathu, esakhiwe ngesisekelo sokutholwa kwe-sulfanylurea, sisebenza kumanyikwe, sivuselela ngobumnene i-b-cell yayo, ebhekele ukukhiqizwa kwe-insulin. Ngaphansi kwethonya lazo, i-pancreas ikhiqiza i-insulin eningi, futhi inani loshukela osegazini liyancipha.
I-Amaryl amaphilisi 2 mg
Ngaphezu kwalokho, into esebenzayo yesidakamizwa nayo isebenza ngezicubu zomzimba, inciphisa ukumelana kwabo ne-insulin. Lokhu kungenxa yokuthi i-glimepiride, ingena esitokisini ngokusebenzisa ulwelwesi, inamandla okuvimba iziteshi ze-potassium. Njengomphumela walesi senzo, amashaneli e-calcium eseli avulekile, i-calcium ingena kwinto yeselula futhi isekele ukukhiqizwa kwe-insulin.
Ngenxa yesenzo esiphindwe kabili, amazinga kashukela egazi anomnene futhi kancane kancane kepha isikhathi eside ancishisiwe. I-Amaryl kanye nama-analogs ayo ahlukile kwizizukulwane ezedlule ngenani elincane lemiphumela emibi, imibango nokukhula okungajwayelekile kwe-hypoglycemia ngenxa yokudla kwabo.
Ifomu Ledosi kanye Ukukhetha Kwedosi
Lesi sidakamizwa, njenganoma iyiphi i-Amaril analogues, sidinga ukulungiswa nokukhethwa kokuhlolwa komthamo odingekayo.
Azikho izimiso ezijwayelekile lapha - isiguli ngasinye sibona umthamo ofanayo walesi sihlukile. Ngakho-ke, ukukhethwa komthamo kwenziwa kuphela ngokubheka ngokucophelela nangokuqhubekayo izinga le-glucose egazini ngemuva komthamo othile womuthi.
Ezinsukwini zokuqala zokwamukelwa, isiguli sinikezwa umthamo okuthiwa yi-Initial wokuqala, okuyi-1 mg ka-Amaril ngosuku. Uma kunesidingo, umthamo wanda kancane kancane, ubhekisisa njalo ushukela. Ukwanda kwenzeka kumiligram eyodwa ngeviki, kaningi - emavikini amabili.
Imvamisa, umthamo omkhulu obekelwe isiguli ngamagremu ayisithupha emithi. Ezimweni ezihlukile kuphela lapho kuvumelekile ukwandisa umthamo wansuku zonke ukuya ku-8 mg, kepha kuyadingeka ukuthatha umuthi lowo ngamanani anjalo ngaphansi kokuqashwa kukachwepheshe.
Izikhala ezingabizi kakhulu nezincazelo
Izindleko zalo muthi ziphezulu impela - kusuka kuma-ruble angama-300 kuye kwangama-800. Ngokunikezwe ukuthi ukuphathwa kwayo kuyaqhubeka, imvamisa kudlula iminyaka eminingi, ukufakwa kwe-Amaril kufanelekile.
Le mishanguzo isuselwa entweni efanayo esebenzayo, kepha ngokuchithwa kwezwe nenkampani ekhiqizayo ingabiza kakhulu kunasekuqaleni. Izidakamizwa ezinjalo zikhiqizwa ezitshalweni zezemithi ePoland, eSlovenia, eNdiya, eHungary, eTurkey, e-Ukraine. Izikhundla ze-Amaril zama-analogues waseRussia zikhiqizwa kabanzi.
Izibhebhe ze-Glimepiride - i-analogue eshibhile kakhulu ye-Amaril
Zihlukile ngegama, ukupakisha, umthamo kanye nezindleko. Isithako esisebenzayo kubo siyefana. Kulokhu, ngendlela, imibuzo elandelayo ayilungile: "Yini engcono i-Amaryl noma i-Glimepiride?" noma "Amaryl and Glimepiride - yini umehluko?"
Iqiniso ngukuthi lawa ngamagama amabili okuhweba nomuthi ofana ncamashi. Ngakho-ke, akulungile ukukhuluma ngobukhulu benye yezindlela ezithile - ziyafana ekwakhiweni nasemphumeleni womzimba.I-glimepiride eyenziwe ngesiRussia eyi-analogue esiseduzane yesidakamizwa.
Kukhiqizwa ngesimo samathebhulethi, ngomthamo wamamiligrama ayi-1, 2, 3 no-4.
Izindleko zalo muthi ziphansi kaningana kune-Amaril uqobo, futhi into esebenzayo ifana ngokuphelele.
Uma ungakwazi ukuyithola, ungathenga iDiamerid. Lezi zibhebhe ziyehluka ngegama negama lomenzi wazo kuphela. Le analogue ye-Amaril nayo ikhiqizwa kumathebulethi ukusuka ku-1 kuye ku-4 mg, kepha ihlukile kweGlepepiride ngentengo ephakeme kancane.
Abenzi bezidakamizwa base-Ukraine banikeza umuthi i-Glimax, cishe onokwakheka okufanayo. Ziyahlukahluka kumthamo - ithebhulethi iqukethe kusuka kuma-milligrams amabili kuya kwamane wezinto ezisebenzayo, amaphilisi we-1 mg awatholakali.
Ithebhulethi Diamerid 2 mg
Futhi, ama-analogues angabizi kakhulu e-Amaril akhiqizwa yizinkampani zemithi zaseNdiya. Amagama abo kwezohwebo yi-Glimed noma i-Glimepiride Aykor. Ithebhulethi elilodwa le-milligram liyatholakala. Ungathola futhi ngokuthengisa isidakamizwa saseNdiya iGlinova.
Umehluko kuphela ukuthi inkampani yokukhiqiza, etholakala eNdiya, iyinkampani esekela inkampani yezidakamizwa yaseBrithani iMaxpharm LTD. Kunamaphilisi ase-Argentina abizwa nge-Glemaz, kodwa maningi amathuba okuba atholakale ikakhulukazi emakhemisi ezweni lethu.
Izinhlu zokukhiqiza kwa-Israyeli, eJordani nase-EU
Uma ngasizathu simbe abathengi bengabethembi abakhiqizi basekhaya noma baseNdiya, ungathenga ama-analogues angabizi kakhulu esikhundleni se-Amaryl, intengo yakho ezoba ephakeme kunaleyo yemikhiqizo yasekhaya, kodwa ephansi kunaleyo yesidakamizwa sokuqala.
Le mishanguzo yenziwa yizinkampani eziseCzech Republic, eHungary, eJordani nakwa-Israyeli. Iziguli zingaqiniseka ngokuphelele ngalezi zidakamizwa - uhlelo lokulawula ikhwalithi yemithi kulawa mazwe luhlukaniswa ngamazinga alo aqinile.
Amaphilisi weGlempid
I-Amix, eyenziwe i-Zentiva, ihlinzekwa ivela eCzech Republic. Umthamo ojwayelekile usukela ku-1 kuya ku-4 amagremu, ukuhlanganiswa kwezinga eliphakeme nezindleko ezifanele uhlukanisa lesi sidakamizwa.
Inkampani yaseHungary eyaziwa ngokuthi i-Egis, egxile kakhulu ezimakethe zeCIS, nayo ikhiqiza i-analogue yayo i-Amarila. Leli thuluzi linegama iGlempid, umthamo ojwayelekile nentengo efanelekile.
IHikma, inkampani enkulu kunazo zonke ekhemisi yaseJordani, eyasungulwa ngo-1978, ibuye yethula nomlingani wayo wase-Amaril, obizwa ngeGlianov. Akudingeki ukhathazeke ngekhwalithi yalo muthi - Imithi yaseJordani yathunyelwa emazweni amaningi omhlaba, kufaka phakathi i-USA, Canada ne-EU, lapho ukulawula izidakamizwa ezingeniswa kukhulu khona.
Abanye abakhiqizi
Ama-genetic alezi zindlela ezidumile zokusekela amazinga kashukela egazi ajwayelekile akhiqizwa nakwamanye amazwe omhlaba.Izitshalo ezenza amakhambi eJalimane, eSlovenia, eLuxembourg, ePoland nase-United Kingdom zikhiqiza izidakamizwa ezahlukahlukene ezithatha indawo ka-Amaryl ngempumelelo. Kodwa-ke, yonke le mishanguzo iyabiza impela, ngakho-ke ayifanele iziguli ezinesabelomali esilinganiselwe.
Izindleko ezinkulu kakhulu, eziphindwe kayishumi ngentengo yabalingani baseRussia noma baseNdiya, yizimali ezikhishwe yizinkampani ezenza imithi eSwitzerland. Kodwa-ke, ukuthola izidakamizwa ezibizayo kanjena akunangqondo kakhulu - ngeke zisebenze kahle, futhi ukuphatha kwazo kubangela imiphumela emibi efanayo njengalabo ababizi abashibhile.
Amavidiyo ahlobene
Imininingwane eminingi ewusizo mayelana ne-Amaril kuvidiyo:
Kukhona nohlu olubanzi lwezidakamizwa ezivela kubakhiqizi abahlukahlukene kanye nezigaba zamanani ahlukahlukene ezithatha indawo ye-Amaryl. Kumele kwaziwe ukuthi lapho ukhetha umuthi, akufanele uthembele entengo ephezulu - akusho ngaso sonke isikhathi ukuthi ikhwalithi efanelekile, kwesinye isikhathi umuthi oshibhile awusebenzi okubi ukwedlula umlingani wawo obiza kakhulu.
