Umuthi i-Lipothioxone uvame ukubekelwa iziguli ezinesifo sikashukela ukuqeda izimpawu ezingezinhle. Izinto ezakha ukwakheka kwazo zisiza ngezindlela ezahlukahlukene ze-polyneuropathy.
Igama Lezwe elingafanele
INN - Thioctic acid.
Umuthi i-Lipothioxone uvame ukubekelwa iziguli ezinesifo sikashukela ukuqeda izimpawu ezingezinhle.
I-ATX
I-A16AX01.
Khipha amafomu nokwakheka
Umuthi uthengiswa ngohlobo lokugxila lapho kulungiswa ikhambi lokufakwa. Ku-1 ampoule yesidakamizwa iqukethe ama-300 noma ama-600 mg wezinto ezisebenzayo i-ALA (alpha-lipoic acid). Ezinye izinto:
- uketshezi lomjovo;
- i-meglumine;
- i-disodium edetate;
- i-anhydrous sodium sulfite;
- i-macrogol (300);
- i-meglumine thioctate (eyakhiwa ukusebenzisana kwe-meglumine ne-thioctic acid).
Umuthi uthengiswa ngohlobo lokugxila lapho kulungiswa ikhambi lokufakwa. Ku-1 ampoule yesidakamizwa iqukethe ama-300 noma ama-600 mg wezinto ezisebenzayo i-ALA (alpha-lipoic acid).
Isenzo se-Pharmacological
I-ALA iyi-antioxidant ye-endo native (ihlinzeka ngesixuku sama-free radicals). Emzimbeni womuntu, le nto yakhiwa yi-oxidation ye-decarboxylated ye-ALPHA-keto acid. Umuthi unikeza ukwehla kwamazinga kashukela kanye nokwanda kokuxineka kwe-glycogen ezinhlakeni zesibindi.
Ingxenye esebenzayo iyafana kumavithamini B. Ithatha iqhaza kulawulo lwe-lipid ne-carbohydrate metabolism, ithuthukisa ukusebenza kwesibindi kanye ne-cholesterol metabolism. Umuthi osuselwa kuwo une-hypoglycemic, hypocholesterolemic kanye ne-lipid-ukunciphisa imiphumela, uzinzisa i-neural trophism.
I-Pharmacokinetics
Ngokusebenzisa umuthi okuphathelene nomuthi, ukuqina kwawo kwe-plasma okuphezulu kufinyelela ku-25-40 μg / ml. I-bioavailability yesidakamizwa ifinyelela kuma-30%. Ihlanganisa futhi i-oxidize esibindini. I-ALA nama-metabolites adalulwa yizinso. Ukuphila kwesigamu kuyahluka kusuka kumaminithi angama-20 kuye kwangama-50.
Izinkomba zokusetshenziswa
- izinhlobo zotshwala nezesifo sikashukela ze-polyneuropathy;
- ukwelashwa nokuvinjwa kwe-coronary atherossteosis;
- i-hepatic pathologies (cirrhosis, isifo seBotkin);
- ukudakwa ngezinto ezahlukahlukene.
I-Hepatic pathologies (cirrhosis, isifo seBotkin) iyisibonakaliso sokusebenzisa umuthi.
Contraindication
- iminyaka engaphansi kweminyaka eyi-18;
- ukungabekezelelani.
Ungayithatha kanjani iLipothioxone?
Umuthi usetshenziswa ngokungenantambo ngendlela ye-infipons infusions. It buhlanjululwe solution isotonic sodium chloride.
Izimo ezinzima ze-polyneuropathic ziphathwa ngemithamo ye-300-600 mg / ngosuku. Isikhathi sokufakwa simayelana nemizuzu engama-45-50. Inkambo ejwayelekile yokwelashwa ingahlala kuze kube ngamaviki ama-4, ngemuva kwalokho i-thioctic acid ibekelwe ukuphathwa ngomlomo. Amacwecwe kufanele aphathwe okungenani izinyanga ezintathu.
Ngoshukela
Iziguli ezinesifo sikashukela i-mellitus zidinga ukuqashwa njalo kwamazinga kashukela lapho usebenzisa umuthi.
Iziguli ezinesifo sikashukela i-mellitus zidinga ukuqashwa njalo kwamazinga kashukela lapho usebenzisa umuthi.
Imiphumela emibi yeLipothioxone
Ngemuva kokulawulwa kwesidakamizwa ukwelashwa kwe-neuropathy yesifo sikashukela, ukukhohliswa kanye ne-diplopia, ukuqubuka kwendawo esikhunjeni, i-purpura, i-thrombocytopathy kanye ne-thrombophlebitis kungavela.
Uma umuthi uphathwa ngokushesha okukhulu. Ukudla ikhanda kanye nezinkinga zokuphefumula kungenzeka. Ukusabela okufanayo okubi kuya ngokwabo.
Ngaphezu kwalokho, ezigulini ezithola lezi infusions, ukubonakaliswa okuhleliwe komzimba we-allergic genesis, ukuvuvukala (kwesikhumba nolwelwesi lwamafinyila), kanye ne-urticaria kwesinye isikhathi kuyabonakala. Kukhona ubungozi be-hypoglycemia ngenxa yokunyuka kokuthathwa koshukela.
Uma kwenzeka kuvela ukuthi kukhona okungahambi kahle, kufanele wazise udokotela wakho ngokushesha. Lokhu kuzogwema izinkinga ezingathandeki.
Uma kwenzeka kuvela ukuthi kukhona okungahambi kahle, kufanele wazise udokotela wakho ngokushesha. Lokhu kuzogwema izinkinga ezingathandeki.
Umthelela ekhonweni lokulawula izindlela
Imithi ayithinti i-psychomotor.
Imiyalo ekhethekile
Lapho usebenzisa umuthi, abanesifo sikashukela badinga ukulawula ukugcwala kweglucose egazini. Kwesinye isikhathi ukulungiswa komthamo kwemithi ye-hypoglycemic kuyadingeka.
Umuthi unezithombe kakhulu, ngakho-ke kufanele ukhishwe ephaketheni ngokushesha ngaphambi kokuwusebenzisa.
Ngesikhathi senqubo yokumnika, kunconywa ukuvikela isixazululo ekukhanyisweni ngosizo lwe-foil noma izikhwama (i-lightproof). Ingxube eseqediwe igcinwa ingasekho amahora angama-6.
Ezimweni ezingapheli zokuphuza, imithamo ikhethwa ngokwahlukahluka kuye ngesisindo, ubudala besiguli kanye nohlobo lwe-pathology.
Sebenzisa ebudaleni
Lezi ziguli zidinga ukukhetha ngokucophelela kwemithamo.
Iziguli esezikhulile zidinga ukukhetha ngokucophelela imithamo.
Isabelo sezingane
Umuthi lo uhlathululwa ezigulini ezingaphansi kweminyaka engu-18.
Sebenzisa ngesikhathi sokukhulelwa nokukhishwa komzimba
Ithuluzi ligwetshwe ngenxa yedatha enganele ekusebenzeni nasekuphepheni kokusebenzisa phakathi nalesi sikhathi.
Isicelo sokusebenza kokulimala kwezinso
Ayisebenzi ezinkingeni ezinkulu zezinso.
Sebenzisa umsebenzi wesibindi okhubazekile
Kusetshenziswe ngokuqapha.
Uma kwenzeka ukungasebenzi kahle kwesibindi, isidakamizwa sisetshenziswa ngokuqapha.
Ukweqisa kweLipothioxone
Uma usebenzisa umuthi isikhathi eside futhi ngemithamo ephezulu, khona-ke ungathola isicanucanu, ukuhlanza kanye nekhanda elibuhlungu.
Ukwelapha ezimweni ezinjalo kuyimpawu. Umuthi awunawo umuthi wokudambisa izidakamizwa.
Ukuxhumana nezinye izidakamizwa
I-Alpha lipoic acid inciphisa umsebenzi we-pharmacotherapeutic we-Cisplatin.
Ngokuhambisana ne-insulin nezinye izidakamizwa ezivela kuma-ejenti amaningi we-hypoglycemic agents, ukwanda komphumela we-hypoglycemic kanye nokukhula kokuvela kwesikhumba kungenzeka.
Ama-ALA amafomu okunzima ukuhlanganisa ukuhlangana kwamamolekyuli kashukela; ngenxa yalokho, umuthi awuhambisani nezixazululo ze-Ringer ne-glucose, kanye nezinto ezingasebenzisana namaqembu we-SH kanye ne-disulfide.
Ukuhambisana notshwala
Ngesikhathi sokulashwa, kuyadingeka ukuyeka ukusetshenziswa kweziphuzo eziqukethe utshwala, ngoba i-ethanol inciphisa umphumela wokwelapha umuthi.
Ngesikhathi sokulashwa, kuyadingeka ukuyeka ukusetshenziswa kweziphuzo eziqukethe utshwala, ngoba i-ethanol inciphisa umphumela wokwelapha umuthi.
Ama-Analog
- I-Berlition;
- Lipamide;
- Neuroleipone;
- I-Thiogma;
- I-Oktolipen;
- I-Tiolepta.
Imibandela yekhefu lekhemisi
Ungathenga umuthi kuphela ngokubhaliwe.
Ngingakwazi ukuthenga ngaphandle kadokotela?
Akunakwenzeka ukuthenga isidakamizwa ngaphandle kwemiyalelo kadokotela. Noma ngabe uyi-oda ku-Intanethi, umuthi uzolethwa ekhemisi eliseduzane, lapho umuthi uzodingeka kumthengi.
Intengo yeLipothioxone
Kusuka kuma-ruble angama-330 ama-ampoules ama-5 we-25 mg. Iphakethe liqukethe nemiyalo yomuthi.
Izimo zokugcina zomuthi
Endaweni engafinyeleleki ezinganeni lapho ukukhanya nomswakama zingatholi.
Umuthi kumele ugcinwe ungafinyeleleki ezinganeni, lapho ukukhanya nomswakama kungatholi.
Isikhathi sokuphelelwa yisikhathi
Kufika ezinyangeni ezingama-24. Isixazululo esilungele ukugcinwa sigcinwa amahora angama-6
Umkhiqizi
IFarmelama Soteks CJSC (Russia).
Ukubuyekezwa kweLipothioxone
U-Irina Skorostrelova (owelaphi), oneminyaka engama-42 ubudala, eMoscow.
Umuthi osebenzayo onomsebenzi owaziwa ngamakhemikhali. Kulokhu, umuthi unomphumela omnene, oqhathaniswa nezitshalo zokwelapha. Isiza ukwelapha ukubonakaliswa kwe-polyneuropathic of etiologies ahlukahlukene (kufaka phakathi labo abanokungadakwa okungapheli). Uma ithuluzi lisabiza kancane, lingabizwa ngokuthi lihamba phambili.
UVladimir Pechenkin, oneminyaka engama-29 ubudala, uVoronezh.
Lokhu kugxiliswa kwezidakamizwa kwanikezwa umama, osenesikhathi eside elashwa isifo sikashukela. Kuqala, saxwayiswa ngemiphumela engemihle ekhonjiswe kwimiyalo yokusebenzisa umuthi, kepha udokotela waqinisekisa, ethi bavele kakhulu futhi uma nje imithetho yezinga lokusebenzisa umuthi ingalandelwa. Wanikeza imijovo uqobo, ngoba isibhedlela esinaso sisekupheleni komgwaqo. Isimo sikamama wami saqala ukuba ngcono kancane, ushukela wabuyela kwesejwayelekile, manje uhlala egcina umuthi kwikhabethe lethu lemithi yasekhaya.
UTatyana Govorova, oneminyaka engama-45, uVologda.
Sengibe yisifo sikashukela iminyaka eminingi. Bengihlala ngesaba ukuzama, ikakhulukazi ngezixazululo zokufaka. Lo muthi unqunywe udokotela wami, wengeza ukuthi kuphephile, kuyasebenza futhi kulula ukuwusebenzisa. Ngibone intuthuko esele ezinsukwini ezi-2 noma ezi-3 ngemuva kokuqala kokwelashwa. Amazinga kashukela egazini abuyele esimweni esijwayelekile, esithuthukisiwe sempilo, futhi nemizwa yathuthuka. Manje angesabi imijovo, ngoba isebenza kakhulu kunamaphilisi.
